We use cookies to give you the best experience possible. By continuing we’ll assume you’re on board with our cookie policy

Foot and mouth disease FMD an infection caused by the food and Paper

Words: 447, Paragraphs: 3, Pages: 2

Paper type: Essay , Subject: Food

Foot and mouth disease (FMD), an infection caused by the food and mouth disease virus (FMDV) is amongst the most contagious trans-boundary viral disease of cloven-hoofed ungulates. The disease has a broader geographical distribution with diverse host species including in domesticated livestock (cattle, pigs, goats and sheep), and susceptible wild artiodactyl with African Buffalo (Syncerus caffer) serving as the reservoir host or persistent carrier for SAT serotypes in Southern African regions.(Paton et al., 2018; Longjam et al., 2011; Wekesa et al., 2015). Outbreak of this infectious virus may results with devastation economic impacts due to the highly expenditures required for disease control, eradication and imposition of strict measures on movement on both domestic and international meat, meat products and livestock trading markets (Knight-Jones and Rushton, 2013).

Besides zooning, the use of vaccines is one of the most feasible and practical method to prevent, control and eradicate potential outbreaks of the FMD (Paton et al., 2009; Depa et al., 2012). The FMDV circulate within seven serotypes: O, A, C, Asia1, South African Territories (SAT1, 2 and 3) and specific serotype can be identified both genetically and serologically. The positive sensed single stranded RNA of the FMD has greater genetic variability, which resulted in the existence of diverse antigenic subtypes within different serotypes (Mittal et al., 2005; Paton et al., 2005). Because vaccination against one serotype of FMDV) does not confers immunity against others serotypes or subtypes of one serotypes (Feng et al., 2016; Paton et al., 2005). The immunogenicity of the current used inactivated whole virus vaccine of the FMDV depend on the wholeness of the most active component of the vaccine, the 146S particle which is the intact virion (Crowther et al., 1995). To date, the most recommended standard testing method to quantify 146S antigen particles is through sucrose density gradient centrifugation (SDG) (Barteling and Meloen, 1974). Even though the SDG can yield good antigen quantification, the test is mostly dependable on the operator, requires expensive instrumentation to run, it quantify only one sample every 5-7 minutes, it is very labour intensive and the detecting instrument cannot be automated. It cannot indicates whether the immunogenic epitopes on VP1 protein of 146S and intact and not degraded by proteases or trypsin effects. (Doel and Mowat, 1985; Van Maanen and Terpstra, 1990).

Don't use plagiarized sources. Get Your Custom Essay on Foot and mouth disease FMD an infection caused by the food and
Just from $13,9/Page

Get Essay

The use Double antibody sandwich-enzyme-linked immunosorbent assay (DAS-ELISA) in detecting the 146S antigen provide greater sensitivity and specificity. DAS-ELISA testing is highly rapid, robust, repeatable and timesaving. This tells allows the quantification of a larger number of sample in relatively fewer times. Most importantly DAS-ELISA is able to determine the integrity of the epitopes on VP1 essential for vaccine potency (Van Maanen and Terpstra, 1990; Feng et al., 2016)

About the author

This sample paper is done by Joseph, whose major is Psychology at Arizona State University. All the content of this work is his research and thoughts on Foot and mouth disease FMD an infection caused by the food and and can be used only as a source of ideas for a similar topic.

Here are other papers written by Joseph:

How to cite this page

Choose cite format:

Foot and mouth disease FMD an infection caused by the food and. (2019, Dec 13). Retrieved from https://paperap.com/foot-and-mouth-disease-fmd-an-infection-caused-by-the-food-and-best-essay/

Is Your Deadline Too Short?
Let Professionals Help You

Get Help

Our customer support team is available Monday-Friday 9am-5pm EST. If you contact us after hours, we'll get back to you in 24 hours or less.

By clicking "Send Message", you agree to our terms of service and privacy policy. We'll occasionally send you account related and promo emails.
No results found for “ image
Try Our service

Hi, I am Colleen from Paperap.

Hi there, would you like to get such a paper? How about receiving a customized one? Click to learn more https://goo.gl/CYf83b